# Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy

> **NCT05180825** · PHASE2 · RECRUITING · sponsor: **University Hospital, Strasbourg, France** · enrollment: 134 (estimated)

## Conditions studied

- Grade 1 Glioma
- Mixed Glio-neuronal Tumors
- Pleomorphic Xanthoastrocytoma

## Interventions

- **DRUG:** Trametinib
- **DRUG:** Vinblastine

## Key facts

- **NCT ID:** NCT05180825
- **Lead sponsor:** University Hospital, Strasbourg, France
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-05-05
- **Primary completion:** 2031-11-01
- **Final completion:** 2031-12-01
- **Target enrollment:** 134 (ESTIMATED)
- **Last updated:** 2025-08-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05180825

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05180825, "Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05180825. Licensed CC0.

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