# Repurposing of Dextromethorphan as an Adjunct Therapy in Patients With Major Depressive Disorder

> **NCT05181527** · PHASE4 · COMPLETED · sponsor: **All India Institute of Medical Sciences, Bhubaneswar** · enrollment: 60 (actual)

## Conditions studied

- Major Depressive Disorder

## Interventions

- **DRUG:** Selective Serotonin Reuptake Inhibitors
- **DRUG:** Dextromethorphan
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05181527
- **Lead sponsor:** All India Institute of Medical Sciences, Bhubaneswar
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-02-10
- **Primary completion:** 2023-09-30
- **Final completion:** 2023-11-30
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2023-12-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05181527

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05181527, "Repurposing of Dextromethorphan as an Adjunct Therapy in Patients With Major Depressive Disorder". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT05181527. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*