# Application of Iced Normal Saline Combined With Cocktail Perfusion in Total Knee Arthroplasty

> **NCT05204056** · NA · COMPLETED · sponsor: **Yantai Yuhuangding Hospital** · enrollment: 60 (actual)

## Conditions studied

- Pain, Postoperative
- Blood Loss, Postoperative

## Interventions

- **DRUG:** iced normal saline
- **DRUG:** Tranexamic acid injection
- **OTHER:** Cocktail (composing by Ropivacaine, Morphine and Epinephrine) perfusion

## Key facts

- **NCT ID:** NCT05204056
- **Lead sponsor:** Yantai Yuhuangding Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-03-02
- **Primary completion:** 2018-06-01
- **Final completion:** 2018-08-01
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2022-01-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05204056

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05204056, "Application of Iced Normal Saline Combined With Cocktail Perfusion in Total Knee Arthroplasty". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05204056. Licensed CC0.

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