# Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology

> **NCT05206955** · PHASE3 · RECRUITING · sponsor: **Mayo Clinic** · enrollment: 80 (estimated)

## Conditions studied

- Fontan Palliation

## Interventions

- **DRUG:** Tadalafil
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05206955
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-09-16
- **Primary completion:** 2026-11
- **Final completion:** 2026-11
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2025-11-14

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05206955

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05206955, "Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT05206955. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*