# The Role of Dopamine, Reward Learning and Prefrontal Activity in Expectation-induced Mood Enhancement

> **NCT05208294** · NA · COMPLETED · sponsor: **Philipps University Marburg** · enrollment: 297 (actual)

## Conditions studied

- Placebo Effect on Mood Improvement

## Interventions

- **DRUG:** Sulpiride 400 MG
- **DRUG:** Placebo
- **BEHAVIORAL:** High expectation manipulation
- **BEHAVIORAL:** Low expectation manipulation

## Key facts

- **NCT ID:** NCT05208294
- **Lead sponsor:** Philipps University Marburg
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-12-09
- **Primary completion:** 2023-09-22
- **Final completion:** 2023-09-22
- **Target enrollment:** 297 (ACTUAL)
- **Last updated:** 2024-01-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05208294

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05208294, "The Role of Dopamine, Reward Learning and Prefrontal Activity in Expectation-induced Mood Enhancement". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05208294. Licensed CC0.

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