# The Impact of Selected Factors on the Cardiovascular System in Chronic Kidney Disease

> **NCT05214872** · — · COMPLETED · sponsor: **Poznan University of Medical Sciences** · enrollment: 252 (actual)

## Conditions studied

- Atherosclerosis of Artery
- Inflammation
- Chronic Kidney Diseases
- Dialysis; Complications
- Cardiovascular Diseases

## Interventions

- **DIAGNOSTIC_TEST:** laboratory parameters - complete blood count
- **OTHER:** body mass index (BMI) [kg/m^2] calculation
- **DIAGNOSTIC_TEST:** selected parameters of oxidative stress (1)
- **DIAGNOSTIC_TEST:** metalloproteinases
- **DIAGNOSTIC_TEST:** parameters of lipids metabolism in the serum
- **DIAGNOSTIC_TEST:** parameters of iron metabolism
- **DIAGNOSTIC_TEST:** selected inflammatory markers
- **DEVICE:** carotid intima-media thickness (IMT)
- **DEVICE:** non-invasive cardiological examinations
- **DEVICE:** vessel stiffness assessment
- **OTHER:** cardiovascular (CV)-related death recording during 2-year follow-up
- **DIAGNOSTIC_TEST:** glucose (Glu)
- **DIAGNOSTIC_TEST:** klotho
- **DIAGNOSTIC_TEST:** fibroblast growth factor 23 (FGF-23)
- **DIAGNOSTIC_TEST:** parameters of calcium and phosphate metabolism
- **DIAGNOSTIC_TEST:** liver enzymes activity assessment
- **DIAGNOSTIC_TEST:** total protein and albumin
- **DIAGNOSTIC_TEST:** creatinine and urea
- **DIAGNOSTIC_TEST:** selected parameters of oxidative stress (2)
- **DIAGNOSTIC_TEST:** selected parameters of oxidative stress (3) sRAGE

## Key facts

- **NCT ID:** NCT05214872
- **Lead sponsor:** Poznan University of Medical Sciences
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2016-03-25
- **Primary completion:** 2020-09-10
- **Final completion:** 2020-09-30
- **Target enrollment:** 252 (ACTUAL)
- **Last updated:** 2022-01-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05214872

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05214872, "The Impact of Selected Factors on the Cardiovascular System in Chronic Kidney Disease". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT05214872. Licensed CC0.

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