# Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults

> **NCT05219968** · PHASE3 · COMPLETED · sponsor: **Lyra Therapeutics** · enrollment: 196 (actual)

## Conditions studied

- Chronic Sinusitis
- Chronic Rhinosinusitis (Diagnosis)

## Interventions

- **DRUG:** LYR-210
- **DRUG:** Sham procedure control
- **OTHER:** Background Therapy

## Key facts

- **NCT ID:** NCT05219968
- **Lead sponsor:** Lyra Therapeutics
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-01-27
- **Primary completion:** 2024-03-04
- **Final completion:** 2024-09-16
- **Target enrollment:** 196 (ACTUAL)
- **Last updated:** 2025-05-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05219968

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05219968, "Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT05219968. Licensed CC0.

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