# SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

> **NCT05222620** · PHASE2 · RECRUITING · sponsor: **Mayo Clinic** · enrollment: 90 (estimated)

## Conditions studied

- Metastatic Malignant Neoplasm in the Brain
- Metastatic Malignant Solid Neoplasm

## Interventions

- **OTHER:** Questionnaire Administration
- **RADIATION:** Stereotactic Radiosurgery
- **RADIATION:** Stereotactic Radiosurgery
- **PROCEDURE:** Magnetic Resonance Imaging

## Key facts

- **NCT ID:** NCT05222620
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-03-14
- **Primary completion:** 2027-02-15
- **Final completion:** 2028-02-15
- **Target enrollment:** 90 (ESTIMATED)
- **Last updated:** 2026-04-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05222620

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05222620, "SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05222620. Licensed CC0.

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