# Influence of Δ9-tetrahydrocannabinol (THC) on Oxycodone Induced Ventilatory Depression in Healthy Volunteers

> **NCT05235503** · PHASE4 · UNKNOWN · sponsor: **Leiden University Medical Center** · enrollment: 20 (estimated)

## Conditions studied

- Respiratory Depression
- Cannabis Use
- Opioid Use

## Interventions

- **DRUG:** Medicinal cannabis in combination with oxycodon
- **DRUG:** Medicinal cannabis in combination with placebo oxycodon

## Key facts

- **NCT ID:** NCT05235503
- **Lead sponsor:** Leiden University Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2021-12-09
- **Primary completion:** 2022-12
- **Final completion:** 2023-06
- **Target enrollment:** 20 (ESTIMATED)
- **Last updated:** 2022-02-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05235503

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05235503, "Influence of Δ9-tetrahydrocannabinol (THC) on Oxycodone Induced Ventilatory Depression in Healthy Volunteers". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05235503. Licensed CC0.

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