# Efficacy and Safety of RTX-GRT7039 in Adult Subjects With Knee Osteoarthritis

> **NCT05248386** · PHASE3 · COMPLETED · sponsor: **Grünenthal GmbH** · enrollment: 469 (actual)

## Conditions studied

- Osteoarthritis

## Interventions

- **DRUG:** RTX-GRT7039
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05248386
- **Lead sponsor:** Grünenthal GmbH
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-08-26
- **Primary completion:** 2024-11-18
- **Final completion:** 2024-11-18
- **Target enrollment:** 469 (ACTUAL)
- **Last updated:** 2026-03-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05248386

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05248386, "Efficacy and Safety of RTX-GRT7039 in Adult Subjects With Knee Osteoarthritis". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05248386. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*