# Clinical Study of Recombinant Humanized CTLA-4-FC Fusion Protein Injection in Healthy Subjects

> **NCT05256719** · PHASE1 · RECRUITING · sponsor: **Beijing VDJBio Co., LTD.** · enrollment: 46 (estimated)

## Conditions studied

- Health Volunteer

## Interventions

- **BIOLOGICAL:** Recombinant human CTLA-4-FC fusion protein for injection 1mg/kg
- **BIOLOGICAL:** Recombinant human CTLA-4-FC fusion protein for injection 2.5mg/kg
- **BIOLOGICAL:** Recombinant human CTLA-4-FC fusion protein for injection 5mg/kg
- **BIOLOGICAL:** Recombinant human CTLA-4-FC fusion protein for injection 7.5mg/kg
- **BIOLOGICAL:** Recombinant human CTLA-4-FC fusion protein for injection 10mg/kg
- **BIOLOGICAL:** Placebo-1mg/kg
- **BIOLOGICAL:** Placebo-2.5mg/kg
- **BIOLOGICAL:** Placebo-5mg/kg
- **BIOLOGICAL:** Placebo-7.5mg/kg
- **BIOLOGICAL:** Placebo-10mg/kg

## Key facts

- **NCT ID:** NCT05256719
- **Lead sponsor:** Beijing VDJBio Co., LTD.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-09-21
- **Primary completion:** 2025-12-31
- **Final completion:** 2025-12-31
- **Target enrollment:** 46 (ESTIMATED)
- **Last updated:** 2024-05-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05256719

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05256719, "Clinical Study of Recombinant Humanized CTLA-4-FC Fusion Protein Injection in Healthy Subjects". Retrieved via AI Analytics 2026-07-05 from https://api.ai-analytics.org/clinical/NCT05256719. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*