# Safety and Pharmacokinetics of Oral Controlled-ileocolonic-release Nicotinamide (CICR-NAM)

> **NCT05258474** · PHASE1 · COMPLETED · sponsor: **University Hospital Schleswig-Holstein** · enrollment: 49 (actual)

## Conditions studied

- Safety Issues
- Pharmacokinetic

## Interventions

- **DRUG:** controlled-ileocolonic-release nicotinamide (SAD/MAD/MD)
- **DRUG:** Immediate-release nicotinamide (SAD)
- **DRUG:** Placebo controlled-ileocolonic-release nicotinamide (SAD/MAD)
- **DRUG:** Placebo Immediate-release nicotinamide (SAD)

## Key facts

- **NCT ID:** NCT05258474
- **Lead sponsor:** University Hospital Schleswig-Holstein
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-12-04
- **Primary completion:** 2022-03-30
- **Final completion:** 2022-03-30
- **Target enrollment:** 49 (ACTUAL)
- **Last updated:** 2022-11-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05258474

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05258474, "Safety and Pharmacokinetics of Oral Controlled-ileocolonic-release Nicotinamide (CICR-NAM)". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05258474. Licensed CC0.

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