# Dengue 4 Human Infection Model (Dengue CVD 11000; DHIM-4)

> **NCT05268302** · PHASE1 · COMPLETED · sponsor: **University of Maryland, Baltimore** · enrollment: 20 (actual)

## Conditions studied

- Dengue

## Interventions

- **BIOLOGICAL:** Dengue 4 Live Virus Human Challenge (DENV-4-LVHC) - Low Dose
- **BIOLOGICAL:** Dengue 4 Live Virus Human Challenge (DENV-4-LVHC) - Low Dose - Homologous Rechallenge

## Key facts

- **NCT ID:** NCT05268302
- **Lead sponsor:** University of Maryland, Baltimore
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-02-28
- **Primary completion:** 2024-01-04
- **Final completion:** 2024-01-04
- **Target enrollment:** 20 (ACTUAL)
- **Last updated:** 2025-04-17

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05268302

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05268302, "Dengue 4 Human Infection Model (Dengue CVD 11000; DHIM-4)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05268302. Licensed CC0.

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