# HBV Vaccination of Healthy Volunteers to Evaluate the Composition of Germinal Centers

> **NCT05272735** · PHASE4 · TERMINATED · sponsor: **Rockefeller University** · enrollment: 9 (actual)

## Conditions studied

- Hepatitis B

## Interventions

- **BIOLOGICAL:** Hepatitis B Vaccine (Recombinant)

## Key facts

- **NCT ID:** NCT05272735
- **Lead sponsor:** Rockefeller University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2022-12-10
- **Primary completion:** 2025-09-29
- **Final completion:** 2025-09-29
- **Target enrollment:** 9 (ACTUAL)
- **Why stopped:** The yield of cells recovered from the lymph node fine needle aspirations was low limiting the ability to perform the planned immunologic assessments following HBV vaccination.
- **Last updated:** 2026-04-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05272735

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05272735, "HBV Vaccination of Healthy Volunteers to Evaluate the Composition of Germinal Centers". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05272735. Licensed CC0.

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