# Predictors of Cognitive Outcomes in Geriatric Depression

> **NCT05273996** · PHASE4 · ACTIVE_NOT_RECRUITING · sponsor: **David Steffens** · enrollment: 75 (estimated)

## Conditions studied

- Major Depressive Disorder
- Neuroticism
- Cognitive Change
- Stress

## Interventions

- **DRUG:** Sertraline, bupropion, desvenlafaxine

## Key facts

- **NCT ID:** NCT05273996
- **Lead sponsor:** David Steffens
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2021-09-28
- **Primary completion:** 2026-06-30
- **Final completion:** 2026-06-30
- **Target enrollment:** 75 (ESTIMATED)
- **Last updated:** 2025-07-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05273996

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05273996, "Predictors of Cognitive Outcomes in Geriatric Depression". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT05273996. Licensed CC0.

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