# Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer

> **NCT05274945** · PHASE2 · COMPLETED · sponsor: **Alexandria University** · enrollment: 58 (actual)

## Conditions studied

- Rectal Cancer

## Interventions

- **RADIATION:** Radiotherapy
- **DRUG:** consolidation chemotherapy
- **PROCEDURE:** TME or APR

## Key facts

- **NCT ID:** NCT05274945
- **Lead sponsor:** Alexandria University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-01-01
- **Primary completion:** 2022-01-01
- **Final completion:** 2022-01-01
- **Target enrollment:** 58 (ACTUAL)
- **Last updated:** 2022-03-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05274945

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05274945, "Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05274945. Licensed CC0.

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