Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer

NCT05276973 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

25

Enrollment

NIH

Sponsor class

Conditions

Fallopian Tube Endometrioid Adenocarcinoma
Fallopian Tube High Grade Serous Adenocarcinoma
Ovarian Endometrioid Adenocarcinoma
Ovarian High Grade Serous Adenocarcinoma
Primary Peritoneal Endometrioid Adenocarcinoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Stage III Fallopian Tube Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage III Primary Peritoneal Cancer AJCC v8
Stage IV Fallopian Tube Cancer AJCC v8
Stage IV Ovarian Cancer AJCC v8
Stage IV Primary Peritoneal Cancer AJCC v8
Unresectable Fallopian Tube Endometrioid Adenocarcinoma
Unresectable Fallopian Tube High Grade Serous Adenocarcinoma
Unresectable Ovarian Endometrioid Adenocarcinoma
Unresectable Ovarian High Grade Serous Adenocarcinoma
Unresectable Primary Peritoneal Endometrioid Adenocarcinoma
Unresectable Primary Peritoneal High Grade Serous Adenocarcinoma

Interventions

PROCEDURE: Biopsy
DRUG: Carboplatin
DRUG: Ipatasertib
DRUG: Paclitaxel

Sponsor

National Cancer Institute (NCI)

Collaborators

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