Relative Bioavailability, Safety, and Tolerability of Single-dose Sotrovimab Injection in Adults (COSMIC)
Stopped Part C cohort 1 was discontinued early in the context of evolving variants with increased fold changes in the in vitro half maximal inhibitory concentration (IC50) and uncertainty in the clinical relevance of these changes.
Conditions
Interventions
- BIOLOGICAL: sotrovimab
- BIOLOGICAL: sotrovimab
- BIOLOGICAL: sotrovimab
- BIOLOGICAL: sotrovimab
- BIOLOGICAL: sotrovimab
- BIOLOGICAL: sotrovimab
- BIOLOGICAL: sotrovimab
Sponsor
Vir Biotechnology, Inc.
Collaborators