# Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

> **NCT05282550** · PHASE2 · RECRUITING · sponsor: **Johns Hopkins University** · enrollment: 100 (estimated)

## Conditions studied

- AMCI - Amnestic Mild Cognitive Impairment
- Sleep Disturbance

## Interventions

- **DRUG:** Trazodone
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05282550
- **Lead sponsor:** Johns Hopkins University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-02-02
- **Primary completion:** 2027-07-30
- **Final completion:** 2028-06-30
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2025-09-18

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05282550

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05282550, "Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT05282550. Licensed CC0.

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