# PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

> **NCT05286814** · PHASE2 · RECRUITING · sponsor: **National Cancer Institute (NCI)** · enrollment: 70 (estimated)

## Conditions studied

- Metastatic Colorectal Cancer (Mcrc)
- Intrahepatic Cholangiocarcinoma (Icc)
- Intrahepatic Bile Duct Cancer
- Colorectal Neoplasms
- Colorectal Cancer
- Cholangiocarcinoma
- Bile Duct Neoplasms
- Bile Duct Cancer
- Adrenocortical Carcinoma (ACC)
- Adrenal Cortical Carcinoma
- Adrenal Gland Cancer
- Adrenal Gland Neoplasms
- Adrenal Cortex Neoplasms

## Interventions

- **DRUG:** Dexamethasone
- **DRUG:** PDS01ADC
- **DEVICE:** Intera 3000 Hepatic Artery Infusion Pump (HAIP)
- **DRUG:** Floxuridine

## Key facts

- **NCT ID:** NCT05286814
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-10-24
- **Primary completion:** 2027-12-31
- **Final completion:** 2028-12-31
- **Target enrollment:** 70 (ESTIMATED)
- **Last updated:** 2026-05-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05286814

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05286814, "PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05286814. Licensed CC0.

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