# An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705

> **NCT05295433** · PHASE1,PHASE2 · RECRUITING · sponsor: **ModernaTX, Inc.** · enrollment: 56 (estimated)

## Conditions studied

- Methylmalonic Acidemia

## Interventions

- **DRUG:** mRNA-3705

## Key facts

- **NCT ID:** NCT05295433
- **Lead sponsor:** ModernaTX, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-03-08
- **Primary completion:** 2034-04-02
- **Final completion:** 2034-04-02
- **Target enrollment:** 56 (ESTIMATED)
- **Last updated:** 2025-12-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05295433

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05295433, "An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT05295433. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*