# Exploration of GCase Activity to Identify a Subpopulation Eligible for a Therapeutic Trial in Dementia With Lewy Bodies

> **NCT05304195** · — · RECRUITING · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 236 (estimated)

## Conditions studied

- Dementia With Lewy Bodies

## Interventions

- **DIAGNOSTIC_TEST:** Glucocerebrosidase
- **GENETIC:** GBA gene
- **DIAGNOSTIC_TEST:** Macrophage biomarkers

## Key facts

- **NCT ID:** NCT05304195
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2023-02-17
- **Primary completion:** 2026-06
- **Final completion:** 2026-06
- **Target enrollment:** 236 (ESTIMATED)
- **Last updated:** 2025-11-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05304195

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05304195, "Exploration of GCase Activity to Identify a Subpopulation Eligible for a Therapeutic Trial in Dementia With Lewy Bodies". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT05304195. Licensed CC0.

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