# Protreat-Trial: Prophylactic Antiemetic Treatment of Opioid-induced Nausea and Vomiting (OINV) in Palliative Care

> **NCT05315999** · PHASE2 · COMPLETED · sponsor: **Gerhild Becker** · enrollment: 30 (actual)

## Conditions studied

- Nausea
- Vomiting
- Pain
- Advanced Cancer

## Interventions

- **DRUG:** Palonosetron Hydrochloride
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05315999
- **Lead sponsor:** Gerhild Becker
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-05-03
- **Primary completion:** 2024-12-18
- **Final completion:** 2024-12-18
- **Target enrollment:** 30 (ACTUAL)
- **Last updated:** 2025-03-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05315999

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05315999, "Protreat-Trial: Prophylactic Antiemetic Treatment of Opioid-induced Nausea and Vomiting (OINV) in Palliative Care". Retrieved via AI Analytics 2026-07-04 from https://api.ai-analytics.org/clinical/NCT05315999. Licensed CC0.

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