A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat

NCT05320380 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

WITHDRAWN

Status

NETWORK

Sponsor class

Stopped Withdrawn per CS0150757

Conditions

Recurrent Acute Myeloid Leukemia
Recurrent B Acute Lymphoblastic Leukemia
Recurrent Mixed Phenotype Acute Leukemia
Recurrent T Acute Lymphoblastic Leukemia
Refractory Acute Myeloid Leukemia
Refractory B Acute Lymphoblastic Leukemia
Refractory Mixed Phenotype Acute Leukemia
Refractory T Acute Lymphoblastic Leukemia

Interventions

DRUG: Anti-CD123 ADC IMGN632
PROCEDURE: Bone Marrow Aspiration and Biopsy
DRUG: Cytarabine
DRUG: Fludarabine Phosphate
DRUG: Hydrocortisone Sodium Succinate
DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
DRUG: Methotrexate
DRUG: Prednisolone

Sponsor

Children's Oncology Group

Collaborators

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