# Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial

> **NCT05322252** · PHASE4 · COMPLETED · sponsor: **Washington University School of Medicine** · enrollment: 30 (actual)

## Conditions studied

- Abortion, Second Trimester
- PPROM
- Rupture, Spontaneous
- Fetal Demise
- Fetal Death
- Fetal Demise From Miscarriage
- Fetal Death Before 22 Weeks With Retention of Dead Fetus
- Pregnancy Loss
- Pregnancy Complications

## Interventions

- **DRUG:** Mifepristone
- **DRUG:** Misoprostol

## Key facts

- **NCT ID:** NCT05322252
- **Lead sponsor:** Washington University School of Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-07-01
- **Primary completion:** 2025-06-14
- **Final completion:** 2025-07-14
- **Target enrollment:** 30 (ACTUAL)
- **Last updated:** 2026-04-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05322252

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05322252, "Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05322252. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
