# A Clinical Study of the Paradise™ Renal Denervation System in Patients With Hypertension (RADIANCE-HTN DUO)

> **NCT05326230** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Otsuka Medical Devices Co., Ltd. Japan** · enrollment: 154 (estimated)

## Conditions studied

- Hypertension
- Vascular Diseases
- Cardiovascular Diseases

## Interventions

- **DEVICE:** Paradise™ (PRDS-001) Renal Denervation Ultrasound System
- **DEVICE:** Renal Angiogram

## Key facts

- **NCT ID:** NCT05326230
- **Lead sponsor:** Otsuka Medical Devices Co., Ltd. Japan
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-07-01
- **Primary completion:** 2026-12
- **Final completion:** 2032-12
- **Target enrollment:** 154 (ESTIMATED)
- **Last updated:** 2026-04-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05326230

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05326230, "A Clinical Study of the Paradise™ Renal Denervation System in Patients With Hypertension (RADIANCE-HTN DUO)". Retrieved via AI Analytics 2026-08-11 from https://api.ai-analytics.org/clinical/NCT05326230. Licensed CC0.

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