# Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU2)

> **NCT05327296** · PHASE3 · COMPLETED · sponsor: **Sedana Medical** · enrollment: 282 (actual)

## Conditions studied

- Sedation

## Interventions

- **DRUG:** Isoflurane
- **DRUG:** Propofol

## Key facts

- **NCT ID:** NCT05327296
- **Lead sponsor:** Sedana Medical
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-06-30
- **Primary completion:** 2024-05-28
- **Final completion:** 2024-11-14
- **Target enrollment:** 282 (ACTUAL)
- **Last updated:** 2026-03-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05327296

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05327296, "Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU2)". Retrieved via AI Analytics 2026-07-09 from https://api.ai-analytics.org/clinical/NCT05327296. Licensed CC0.

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