Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
Conditions
- Metastatic Renal Cell Carcinoma
- Stage III Renal Cell Cancer AJCC v8
- Stage IV Renal Cell Cancer AJCC v8
- Unresectable Renal Cell Carcinoma
Interventions
- BIOLOGICAL: Avelumab
- DRUG: Axitinib
- PROCEDURE: Biospecimen Collection
- PROCEDURE: Bone Scan
- DRUG: Cabozantinib
- PROCEDURE: Computed Tomography
- BIOLOGICAL: Ipilimumab
- DRUG: Lenvatinib
- PROCEDURE: Magnetic Resonance Imaging
- BIOLOGICAL: Nivolumab
- BIOLOGICAL: Pembrolizumab
- RADIATION: Stereotactic Ablative Radiotherapy
Sponsor
NRG Oncology
Collaborators