# Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck Chemoradiotherapy: A Phase 2, Simon 2-stage Trial

> **NCT05331131** · PHASE2 · WITHDRAWN · sponsor: **Northwell Health**

## Conditions studied

- Cancer of Head and Neck
- Mucositis Oral
- Pharyngeal Mucositis

## Interventions

- **DRUG:** Ketamine Topical

## Key facts

- **NCT ID:** NCT05331131
- **Lead sponsor:** Northwell Health
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2022-09-19
- **Primary completion:** 2025-05-01
- **Final completion:** 2025-11-14
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Study team not moving forward with protocol
- **Last updated:** 2024-01-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05331131

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05331131, "Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck Chemoradiotherapy: A Phase 2, Simon 2-stage Trial". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT05331131. Licensed CC0.

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