# Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.

> **NCT05333523** · PHASE3 · RECRUITING · sponsor: **Radboud University Medical Center** · enrollment: 242 (estimated)

## Conditions studied

- Laryngeal Squamous Cell Carcinoma
- Hypopharynx Squamous Cell Carcinoma
- Oropharyngeal Squamous Cell Carcinoma

## Interventions

- **RADIATION:** Sentinel lymph node biopsy guided selective elective neck irradiation
- **RADIATION:** Standard elective neck irradiation

## Key facts

- **NCT ID:** NCT05333523
- **Lead sponsor:** Radboud University Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-12-06
- **Primary completion:** 2029-12-01
- **Final completion:** 2029-12-01
- **Target enrollment:** 242 (ESTIMATED)
- **Last updated:** 2025-11-24

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05333523

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05333523, "Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05333523. Licensed CC0.

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