# Efficacy of VTP-300 in Chronic Hepatitis B Infection

> **NCT05343481** · PHASE2 · COMPLETED · sponsor: **Barinthus Biotherapeutics** · enrollment: 121 (actual)

## Conditions studied

- Chronic Hepatitis B

## Interventions

- **BIOLOGICAL:** ChAdOx1-HBV
- **BIOLOGICAL:** MVA-HBV
- **BIOLOGICAL:** Nivolumab

## Key facts

- **NCT ID:** NCT05343481
- **Lead sponsor:** Barinthus Biotherapeutics
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-09-21
- **Primary completion:** 2026-01-13
- **Final completion:** 2026-01-13
- **Target enrollment:** 121 (ACTUAL)
- **Last updated:** 2026-04-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05343481

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05343481, "Efficacy of VTP-300 in Chronic Hepatitis B Infection". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05343481. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*