# A Phase 1 Dose Escalation Study of Oral VX-708 in Healthy Participants

> **NCT05347394** · PHASE1 · COMPLETED · sponsor: **Vertex Pharmaceuticals Incorporated** · enrollment: 100 (actual)

## Conditions studied

- Acute Pain

## Interventions

- **DRUG:** VX-708
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05347394
- **Lead sponsor:** Vertex Pharmaceuticals Incorporated
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-04-08
- **Primary completion:** 2023-04-14
- **Final completion:** 2023-04-14
- **Target enrollment:** 100 (ACTUAL)
- **Last updated:** 2023-05-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05347394

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05347394, "A Phase 1 Dose Escalation Study of Oral VX-708 in Healthy Participants". Retrieved via AI Analytics 2026-06-13 from https://api.ai-analytics.org/clinical/NCT05347394. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*