Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants

NCT05364762 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

20

Enrollment

OTHER

Sponsor class

Conditions

Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Chronic Myelomonocytic Leukemia
Myelodysplastic Syndrome
Myeloproliferative Neoplasm
Primary Myelofibrosis
Secondary Myelofibrosis

Interventions

DRUG: Cyclophosphamide
DRUG: Itacitinib
PROCEDURE: Peripheral Blood Stem Cell Transplantation
OTHER: Quality-of-Life Assessment
DRUG: Tacrolimus

Sponsor

City of Hope Medical Center

Collaborators

[object Object]