# A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa

> **NCT05373758** · NA · RECRUITING · sponsor: **Massachusetts General Hospital** · enrollment: 648 (estimated)

## Conditions studied

- HIV Infections
- AIDS
- Virologic Failure

## Interventions

- **OTHER:** Standard of Care treatment strategy
- **OTHER:** Individualized Care treatment strategy
- **OTHER:** Immediate Switch

## Key facts

- **NCT ID:** NCT05373758
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-02-07
- **Primary completion:** 2027-06-30
- **Final completion:** 2027-06-30
- **Target enrollment:** 648 (ESTIMATED)
- **Last updated:** 2026-03-19

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05373758

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05373758, "A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT05373758. Licensed CC0.

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