Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin

NCT05375825 · clinicaltrials.gov ↗

PHASE1

Phase

WITHDRAWN

Status

NIH

Sponsor class

Stopped No participants enrolled.

Conditions

Malignant Pleural Mesotheliomas (Mpm)
Malignant Pleural Effusions (Mpe)
Epithelial Tumors, Malignant
Pleural Effusions, Malignant
Mesothelin (Msln)

Interventions

PROCEDURE: Cytoreductive surgery
DRUG: LMB-100
DIAGNOSTIC_TEST: Immunohistochemical Assay for Mesothelin

Sponsor

National Cancer Institute (NCI)