# An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

> **NCT05376878** · PHASE4 · RECRUITING · sponsor: **City of Hope Medical Center** · enrollment: 10 (estimated)

## Conditions studied

- Anatomic Stage IV Breast Cancer AJCC v8
- Metastatic Breast Carcinoma
- Metastatic Malignant Neoplasm in the Brain

## Interventions

- **OTHER:** Copper Cu 64-DOTA-Trastuzumab
- **PROCEDURE:** Magnetic Resonance Imaging
- **DEVICE:** Positron Emission Tomography
- **BIOLOGICAL:** Trastuzumab
- **BIOLOGICAL:** Trastuzumab Deruxtecan

## Key facts

- **NCT ID:** NCT05376878
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-12-21
- **Primary completion:** 2026-05-26
- **Final completion:** 2026-05-26
- **Target enrollment:** 10 (ESTIMATED)
- **Last updated:** 2026-02-23

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05376878

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05376878, "An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis". Retrieved via AI Analytics 2026-07-13 from https://api.ai-analytics.org/clinical/NCT05376878. Licensed CC0.

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