# Feasibility and Safety of autoloGous UncondItioneD pEripheral Nerve Tissue Delivery to the Substantia Nigra (GUIDE)

> **NCT05377281** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Craig van Horne, MD, PhD** · enrollment: 10 (estimated)

## Conditions studied

- Parkinson's Disease

## Interventions

- **PROCEDURE:** Peripheral Nerve Tissue Implantation

## Key facts

- **NCT ID:** NCT05377281
- **Lead sponsor:** Craig van Horne, MD, PhD
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-07-07
- **Primary completion:** 2027-06-30
- **Final completion:** 2027-06-30
- **Target enrollment:** 10 (ESTIMATED)
- **Last updated:** 2025-10-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05377281

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05377281, "Feasibility and Safety of autoloGous UncondItioneD pEripheral Nerve Tissue Delivery to the Substantia Nigra (GUIDE)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05377281. Licensed CC0.

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