# Bevonescein for Intra-Operative Nerve Visualization in Head and Neck Surgery

> **NCT05377554** · PHASE3 · COMPLETED · sponsor: **Alume Biosciences, Inc.** · enrollment: 154 (actual)

## Conditions studied

- Surgery

## Interventions

- **DRUG:** Bevonescein
- **OTHER:** Intraoperative Visualization using White Light Reflectance (WLR) with Fluorescence (FL) Overlay
- **OTHER:** Intra-operative Visualization using White Light Reflectance (WLR)

## Key facts

- **NCT ID:** NCT05377554
- **Lead sponsor:** Alume Biosciences, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-04-29
- **Primary completion:** 2025-10-27
- **Final completion:** 2025-11-24
- **Target enrollment:** 154 (ACTUAL)
- **Last updated:** 2026-04-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05377554

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05377554, "Bevonescein for Intra-Operative Nerve Visualization in Head and Neck Surgery". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT05377554. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*