# Ketamine for Multiple Sclerosis Fatigue

> **NCT05378100** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Johns Hopkins University** · enrollment: 110 (estimated)

## Conditions studied

- Multiple Sclerosis Fatigue

## Interventions

- **DRUG:** Ketamine
- **DRUG:** Midazolam

## Key facts

- **NCT ID:** NCT05378100
- **Lead sponsor:** Johns Hopkins University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-01-01
- **Primary completion:** 2026-06-01
- **Final completion:** 2026-10-01
- **Target enrollment:** 110 (ESTIMATED)
- **Last updated:** 2026-03-20

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05378100

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05378100, "Ketamine for Multiple Sclerosis Fatigue". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT05378100. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*