# SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder

> **NCT05378399** · PHASE3 · COMPLETED · sponsor: **Brigham and Women's Hospital** · enrollment: 40 (actual)

## Conditions studied

- HIV Infections
- Substance Use
- Adherence, Medication
- Adherence, Treatment

## Interventions

- **DRUG:** Descovy or Truvada
- **DEVICE:** ID-Cap System
- **DEVICE:** Beiwe

## Key facts

- **NCT ID:** NCT05378399
- **Lead sponsor:** Brigham and Women's Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-12-20
- **Primary completion:** 2026-02-27
- **Final completion:** 2026-02-27
- **Target enrollment:** 40 (ACTUAL)
- **Last updated:** 2026-04-28

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05378399

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05378399, "SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05378399. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*