# The CyberChallenge Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases?

> **NCT05378633** · NA · RECRUITING · sponsor: **University Hospital Heidelberg** · enrollment: 190 (estimated)

## Conditions studied

- Brain Metastases
- Nsclc

## Interventions

- **RADIATION:** SRS
- **RADIATION:** Whole Brain Radiotherapy

## Key facts

- **NCT ID:** NCT05378633
- **Lead sponsor:** University Hospital Heidelberg
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-02-24
- **Primary completion:** 2027-02-24
- **Final completion:** 2028-02-24
- **Target enrollment:** 190 (ESTIMATED)
- **Last updated:** 2026-03-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05378633

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05378633, "The CyberChallenge Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases?". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT05378633. Licensed CC0.

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