# Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer

> **NCT05378919** · PHASE2 · RECRUITING · sponsor: **Lithuanian University of Health Sciences** · enrollment: 250 (estimated)

## Conditions studied

- Neoadjuvant Therapy in Rectal Cancer, Radiotherapy, FOLFOX

## Interventions

- **RADIATION:** Radiotherapy 50 Gy
- **DRUG:** Fluorouracil/folic acid
- **DRUG:** Chemotherapy in regimen with Oxaliplatin, fluorouracil, folinic acid (FOLFOX4)
- **RADIATION:** Radiotherapy 50 Gy

## Key facts

- **NCT ID:** NCT05378919
- **Lead sponsor:** Lithuanian University of Health Sciences
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2015-06-01
- **Primary completion:** 2025-06-01
- **Final completion:** 2027-06-01
- **Target enrollment:** 250 (ESTIMATED)
- **Last updated:** 2022-05-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05378919

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05378919, "Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05378919. Licensed CC0.

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