# A Study of AK112 With or Without AK117 in Metastatic Colorectal Cancer

> **NCT05382442** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Akeso** · enrollment: 254 (estimated)

## Conditions studied

- Metastatic Colorectal Cancer

## Interventions

- **DRUG:** AK112
- **DRUG:** AK117
- **DRUG:** Oxaliplatin
- **DRUG:** Capecitabine
- **DRUG:** Irinotecan
- **DRUG:** Leucovorin
- **DRUG:** 5-fluorouracil

## Key facts

- **NCT ID:** NCT05382442
- **Lead sponsor:** Akeso
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-06-27
- **Primary completion:** 2026-05-15
- **Final completion:** 2028-08-12
- **Target enrollment:** 254 (ESTIMATED)
- **Last updated:** 2025-10-14

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05382442

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05382442, "A Study of AK112 With or Without AK117 in Metastatic Colorectal Cancer". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT05382442. Licensed CC0.

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