# Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile

> **NCT05389904** · NA · RECRUITING · sponsor: **Brigham and Women's Hospital** · enrollment: 300 (estimated)

## Conditions studied

- C. Difficile

## Interventions

- **OTHER:** Arm 1: Routine care
- **OTHER:** Arm 2: Preemptive C. difficile infection prevention bundle

## Key facts

- **NCT ID:** NCT05389904
- **Lead sponsor:** Brigham and Women's Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-07-25
- **Primary completion:** 2025-06-01
- **Final completion:** 2026-08
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2026-03-04

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05389904

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05389904, "Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile". Retrieved via AI Analytics 2026-07-05 from https://api.ai-analytics.org/clinical/NCT05389904. Licensed CC0.

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