# Brain Stimulation for Severe Depression

> **NCT05393622** · NA · RECRUITING · sponsor: **Inner Cosmos Inc** · enrollment: 20 (estimated)

## Conditions studied

- Depression Severe

## Interventions

- **DEVICE:** INTRACALVARIAL PREFRONTAL CORTICAL STIMULATION (IpCS) IN SEVERE TREATMENT-RESISTANT DEPRESSION

## Key facts

- **NCT ID:** NCT05393622
- **Lead sponsor:** Inner Cosmos Inc
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-07-28
- **Primary completion:** 2026-12
- **Final completion:** 2027-12
- **Target enrollment:** 20 (ESTIMATED)
- **Last updated:** 2026-04-15

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05393622

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05393622, "Brain Stimulation for Severe Depression". Retrieved via AI Analytics 2026-07-05 from https://api.ai-analytics.org/clinical/NCT05393622. Licensed CC0.

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