# Base Edited CAR7 T Cells to Treat T Cell Malignancies (TvT CAR7)

> **NCT05397184** · PHASE1 · UNKNOWN · sponsor: **Great Ormond Street Hospital for Children NHS Foundation Trust** · enrollment: 10 (estimated)

## Conditions studied

- Relapsed/Refractory T-cell Acute Lymphoid Leukaemia

## Interventions

- **BIOLOGICAL:** Cryopreserved BE CAR7 T cells (BE752TBCCLCAR7PBL)

## Key facts

- **NCT ID:** NCT05397184
- **Lead sponsor:** Great Ormond Street Hospital for Children NHS Foundation Trust
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-04-19
- **Primary completion:** 2024-04-01
- **Final completion:** 2025-02-28
- **Target enrollment:** 10 (ESTIMATED)
- **Last updated:** 2023-07-05

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05397184

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05397184, "Base Edited CAR7 T Cells to Treat T Cell Malignancies (TvT CAR7)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05397184. Licensed CC0.

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