# Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis

> **NCT05398679** · PHASE4 · RECRUITING · sponsor: **Fundacion Clinic per a la Recerca Biomédica** · enrollment: 360 (estimated)

## Conditions studied

- Endocarditis Infective

## Interventions

- **DRUG:** Cefaclor
- **DRUG:** Ciprofloxacin Tablets
- **DRUG:** Ciprofloxacin Injection
- **DRUG:** Clindamycin Oral Capsule
- **DRUG:** Clindamycin Injection
- **DRUG:** Dicloxacillin Oral Capsule
- **DRUG:** Dicloxacillin
- **DRUG:** Fusidic Acid Only Product in Oral Dose Form
- **DRUG:** Fusidic Acid Only Product in Parenteral Dose Form
- **DRUG:** Levofloxacin Oral Tablet
- **DRUG:** Levofloxacin Injection
- **DRUG:** Linezolid Oral Tablet
- **DRUG:** Linezolid Injectable Product
- **DRUG:** Moxifloxacin tablet
- **DRUG:** Moxifloxacin Injectable Product
- **DRUG:** Rifampicin Only Product in Oral Dose Form
- **DRUG:** Rifampicin Only Product in Parenteral Dose Form
- **DRUG:** Sulfamethoxazole / Trimethoprim Oral Tablet [Bactrim]
- **DRUG:** Sulfamethoxazole / Trimethoprim Injectable Product
- **DRUG:** Tedizolid Oral Tablet

## Key facts

- **NCT ID:** NCT05398679
- **Lead sponsor:** Fundacion Clinic per a la Recerca Biomédica
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-08-17
- **Primary completion:** 2026-12-30
- **Final completion:** 2027-12-30
- **Target enrollment:** 360 (ESTIMATED)
- **Last updated:** 2026-02-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05398679

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05398679, "Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05398679. Licensed CC0.

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