# Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD

> **NCT05398757** · NA · WITHDRAWN · sponsor: **Osijek University Hospital**

## Conditions studied

- Postoperative Cognitive Dysfunction
- Postoperative Pain, Acute
- Pertrochanteric Fracture

## Interventions

- **BEHAVIORAL:** Mini mental state exame (MMSE)
- **BEHAVIORAL:** Digit Symbol Substitution Test (DSST)
- **DIAGNOSTIC_TEST:** Numeric rating Scale (NRS)
- **DIAGNOSTIC_TEST:** Postoperative inflammation
- **DRUG:** Midazolam
- **DRUG:** Propofol
- **DRUG:** Dexmedetomidin

## Key facts

- **NCT ID:** NCT05398757
- **Lead sponsor:** Osijek University Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2022-07-01
- **Primary completion:** 2024-03-01
- **Final completion:** 2024-03-01
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Too long recruitment period due to small number of patients
- **Last updated:** 2024-09-19

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05398757

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05398757, "Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT05398757. Licensed CC0.

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