# The Role of Neurofilament Light (NfL) in Patients With Hydrocephalus

> **NCT05399602** · NA · COMPLETED · sponsor: **University Hospital Hradec Kralove** · enrollment: 41 (actual)

## Conditions studied

- Hydrocephalus
- Brain Damage
- General Anesthetics Toxicity

## Interventions

- **DIAGNOSTIC_TEST:** Lumbar puncture
- **DIAGNOSTIC_TEST:** External lumbar drainage
- **DIAGNOSTIC_TEST:** Lumbar infusion test
- **PROCEDURE:** Ventriculo-peritoneal shunt placement
- **PROCEDURE:** General Anesthesia
- **PROCEDURE:** Prechamber puncture
- **PROCEDURE:** Blood sampling #1
- **PROCEDURE:** Blood sampling #2
- **PROCEDURE:** Blood sampling #3
- **PROCEDURE:** Blood sampling #4 and #5

## Key facts

- **NCT ID:** NCT05399602
- **Lead sponsor:** University Hospital Hradec Kralove
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-12-07
- **Primary completion:** 2025-09-27
- **Final completion:** 2025-09-27
- **Target enrollment:** 41 (ACTUAL)
- **Last updated:** 2025-10-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05399602

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05399602, "The Role of Neurofilament Light (NfL) in Patients With Hydrocephalus". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT05399602. Licensed CC0.

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