# Natural History in Children up to 16 Years With Mild to Profound Hearing Loss Due to Mutations in GJB2 / OTOF Genes

> **NCT05402813** · — · RECRUITING · sponsor: **Sensorion** · enrollment: 180 (estimated)

## Conditions studied

- Sensorineural Hearing Loss, Bilateral
- AUNB1
- DFNB1A
- Congenital Deafness
- DFNB9
- OTOF Gene Mutation
- GJB2 Gene Mutation

## Interventions

- **OTHER:** Pure Tone Audiometry Assessment
- **OTHER:** Quality of Life Questionnaires

## Key facts

- **NCT ID:** NCT05402813
- **Lead sponsor:** Sensorion
- **Sponsor class:** INDUSTRY
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2022-11-18
- **Primary completion:** 2028-11-18
- **Final completion:** 2028-11-18
- **Target enrollment:** 180 (ESTIMATED)
- **Last updated:** 2026-04-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05402813

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05402813, "Natural History in Children up to 16 Years With Mild to Profound Hearing Loss Due to Mutations in GJB2 / OTOF Genes". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT05402813. Licensed CC0.

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